Recent Activity

GMDx Genomics Publications
2019

Steele EJ., and Lindley RA. (2019) Regulatory T cells and co-evolution of allele-specific MHC recognition by the TCR. Scandinavian Journal of Immunology. In Review; copy available upon request.

 

Lindley RA. (2019) Deaminase Targeted Somatic Mutation (TSM) Signatures: A Review Targeted Codon-Context DNA and RNA Deamination Mutations in Cancer Genome Diagnosis and Prognosis. Mutation Research. In Preparation.

Franklin A, Steele EJ, Lindley RA. (2019) A proposed reverse transcription mechanism for (CAG)n and similar expandable repeats that cause neurological and other diseases. Heliyon (submitted and under review; copy available upon request).

Mamrot J, Balachandran S, Steele EJ, Lindley RA. (2019) Molecular model linking Th2 polarized M2 tumour-associated macrophages with deaminase-mediated cancer progression mutation signatures. Scandinavian Journal of Immunology, 89(5): e12760. DOI: 10.1111/sji.12760.

Hall NE, Mamrot J, Frampton CMA, Read P, Steele EJ, Bischof RJ, Lindley RA. (2019) Deaminase associated single nucleotide variants in blood and saliva-derived exomes from healthy subjects. BMC Medical Genomics (submitted and under review; copy available upon request).

Lindley RA and Steele EJ. (2019) Deaminases and Why Mice Sometimes Lie in Immuno-Oncology Pre-Clinical Trials. Annals of Clinical Oncology, 2(1): pp2-5. DOI: 10.31487/j.ACO.2019.01.001.

Lindley RA. (2019) Deaminase Targeted Somatic Mutation (TSM) Signatures: A Review Targeted Codon-Context DNA and RNA Deamination Mutations in Cancer Genome Diagnosis and Prognosis. Mutation Research (submitted and under review; copy available on request)

Steele E, Gorczynski R, Lindley RA, Liu Y, Temple R, Tokoro G, Wickramasinghe D, Wickramasingh C. (2019) Lamarck and Panspermia: Environmentally-Induced Rapid Directional Genetic Adaptation and the Effective Spread of Living Systems Throughout the Cosmos. In Press, Progress in Biophysics and Molecular Biology. DOI: 10.1016/j.pbiomolbio.2019.08.010.

Published Patents

Recently filed

Lindley RA, Hall NE, Mamrot J. (2019) Methods for diagnosis and treatment of neurodegenerative disorders .PCT Provisional Patent Application number WO201990402

Hall NE, Mamrot J, Lindley RA. (2019) Systems and methods for predicting the efficacy of cancer therapy. https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2019095017.

 

Lindley RA. (2019) Cell sampling apparatus, kit and method. https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2019056060.

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