Publications

2021
Mamrot J, Hall E, Lindley RA. (2021) Identification and validation model to identify cancer progression signatures in multiple cancers. Oncotarget, 12(8). https://www.oncotarget.com/article/27934/
2020
Lindley RA. (2020) A Review of the mutational role of deaminases and the generation of a cognate molecular model to explain cancer mutation spectra. Medical Research Archives, 8(8). https://journals.ke-i.org/mra/article/view/2177
Hall NE, Mamrot J, Steele EJ, Frampton C, Read P, Bischoff R, Lindley RA. (2020) Blood and saliva-derived exomes from healthy Caucasian subjects do not display overt evidence of somatic mosaicism. Mut Res Fund Mech Mutagen 821 (2020) 111705
https://doi.org/10.1016/j.mrfmmm.2020.111705
2019
Mamrot J, Balachandran S, Steele EJ, Lindley RA. (2019) Molecular model linking Th2 polarized M2 tumour-associated macrophages with deaminase-mediated cancer progression mutation signatures. Scandinavian Journal of Immunology, 89(5): e12760. doi: 10.1111/sji.12760.
Lindley RA and Steele EJ. (2019) Deaminases and Why Mice Sometimes Lie in Immuno-Oncology Pre-Clinical Trials. Annals of Clinical Oncology. 2(1): pp2-5. doi: 10.31487/j.ACO.2019.01.001.
2018
Lindley RA, Hall NE. (2018) APOBEC and ADAR deaminases may cause many single nucleotide polymorphisms curated in the OMIM database. Mutation Research. 810(1): pp33-38. doi: 10.1016/j.mrfmmm.2018.03.008.
Steele EJ, Lindley RA. (2018) Germline V repertoires: Origin, maintenance, diversification. Scandinavian Journal of Immunology. 87(6): e12670. doi: 10.1111/sji.12670.
2017
Steele EJ and Lindley RA. (2017) ADAR deaminase A-to-I editing of DNA and RNA moieties
of RNA:DNA hybrids has implications for the mechanism of Ig somatic hypermutation. DNA Repair. 55(1): pp1-6. doi: 10.1016/j.dnarep.2017.04.004.
2016
Lindley RA, Humbert P, Larner C, Akmeemana EH, Pendlebury CR. (2016) Association between targeted somatic mutation (TSM) signatures and HGS-OvCa progression. Cancer Medicine. 5(9): pp2629-2640. doi: 10.1002/cam4.825.
2013
Lindley RA. (2013) The importance of codon context for understanding the Ig-like somatic hypermutation strand-biased patterns in TP53 mutations in breast cancer. Cancer Genetics. 206(6): pp222-6. doi: 10.1016/j.cancergen.2013.05.016.
Lindley RA and Steele EJ. (2013) Critical analysis of strand-biased somatic mutation signatures in TP53 versus Ig genes, in genome -wide data and the etiology of cancer. International Scholarly Research Notices: Genetics. Article ID: 921418. doi: 10.1155/2013/921418.
2011
Steele EJ, Lindley RA, Weiller GW. (2011) Somatic hypermutation and the discovery of A-to-I RNA editing sites? Biochemical and Biophysical Research Communications. 414(2): p443. doi: 10.1016/j.bbrc.2011.09.111.
2010
Steele EJ, Lindley RA. (2010) Somatic mutation patterns in non-lymphoid cancers resemble the strand biased somatic hypermutation spectra of antibody genes. DNA Repair. 9(6): pp600-603. doi: 10.1016/j.dnarep.2010.03.007.
2006
Steele EJ, Lindley RA, Wen J, Weiller GF. (2006) Computational analyses show A-to-G mutations correlate with nascent mRNA hairpins at somatic hypermutation hotspots. DNA Repair. 5(11): pp1346-1363. doi: 10.1016/j.dnarep.2006.06.002.